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Blood clot
Closeup of woman hands holding and massaging her calf, suffering from calf pain. Calf pain may be muscle-related diagnoses, there are some potentially serious ones , like a blood clot or claudication.
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This is a more serious case. Leg swelling, both or usually one, can indicate a blood clot in the tissue, also called deep vein thrombosis (DVT). “This can happen at any age, and it typically happens after someone has been laid up after an injury or hospitalization, or after a long car ride or airplane flight,” says Dr. Tonnessen.
Symptoms that accompany the swelling may include
Senior woman swollen feet and leg
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pain
tenderness
a warm sensation
redness or color change in the affected area
fever

Diagnosis
General physical examination for the lower limbs