Action: If leg pain persists >2 weeks with no clear cause—and especially if paired with fatigue, appetite loss, or back pain—mention it to your doctor.
🩹 3. Strange Rash on Shins: Necrolytic Migratory Erythema (NME)
What it looks like:
Red, blistering, scaly rash on shins, groin, or feet
Lesions that heal in one spot and reappear elsewhere
Skin that cracks, bleeds, or looks infected—but doesn’t respond to creams
Why it matters:
This rare rash is strongly linked to glucagonoma—a rare pancreatic neuroendocrine tumor that overproduces the hormone glucagon. NME is often the first visible clue.
🧪 Dermatologists sometimes diagnose internal cancer based on this rash alone.
